This inventor holds 1 USPTO granted patent. Top assignee: Cell Signaling Technology, Inc.. Active years: 2011.
Company Filing History:
Years Active: 2011
Title: The Innovative Contributions of Hong Ruan
Introduction
Hong Ruan is an accomplished inventor residing in Middleton, MA. With his significant contributions to the field of biomedical research, Ruan has earned recognition for his innovative invention related to ATR kinase detection. His patent highlights his expertise and commitment to advancing scientific knowledge.
Latest Patents
Hong Ruan holds a patent titled "Reagents for the detection of phosphorylated ATR kinase (Ser 428) and uses thereof." This groundbreaking invention discloses two novel phosphorylation sites in human ATR kinase, specifically serine 428 (Ser428) and serine 2317 (Ser2317). The patented reagents, which comprise antibodies and AQUA peptides, are designed to selectively bind to ATR kinase only when phosphorylated at these specific sites, thereby allowing for precise detection. Additionally, the invention outlines methods for assessing ATR kinase phosphorylation in biological samples, utilizing detectable reagents that bind selectively to ATR when phosphorylated. The patent also includes kits featuring the ATR (Ser428, Ser2317)-specific reagents, further showcasing the practical applications of Ruan’s innovation.
Career Highlights
Hong Ruan's career is marked by his role at Cell Signaling Technology, Inc., where he continues to contribute to the development of cutting-edge technologies in the field of signal transduction research. His experience and dedication to research have placed him at the forefront of innovative solutions in detecting and analyzing protein phosphorylation.
Collaborations
Throughout his career, Ruan has collaborated with notable professionals in his field, including colleagues Mark Livingstone and Robert Polakiewicz. These collaborations have fostered an environment of innovation and have contributed to the success of various research initiatives aimed at better understanding cell signaling mechanisms.
Conclusion
Hong Ruan’s inventive contributions in the detection of phosphorylated ATR kinase underscore his significant role in advancing biomedical research. His dedication to developing specialized reagents and methods is pivotal in enhancing our understanding of protein functions and associated diseases. As he continues to innovate, Ruan exemplifies the spirit of invention that drives scientific progress forward.