Hong-Ming Shieh

Title: Innovations of Hong-Ming Shieh

Introduction

Hong-Ming Shieh is a notable inventor based in Langhorne, PA (US). He has made significant contributions to the field of biochemistry, particularly in the stabilization of proteins and polypeptides. With a total of 7 patents to his name, his work has had a considerable impact on pharmaceutical compositions.

Latest Patents

One of his latest patents is focused on the "Stabilization of fibroblast growth factors by modification of cysteine." This invention relates to physiologically-active derivatized natural and recombinant mammalian and human proteins and polypeptides. The invention provides chemical methods for derivatizing proteins or polypeptides containing cysteine residues, either naturally or through site-specific mutagenesis. The pharmaceutical compositions containing these derivatized proteins and/or polypeptides are formulated to provide stable, long-acting compositions, which were previously difficult to achieve. Another significant patent is the "Stabilization of somatotropins and other proteins by modification of cysteine," which shares similar methodologies and applications as the first.

Career Highlights

Hong-Ming Shieh is currently associated with American Cyanamid Company, where he continues to innovate in the field of protein stabilization. His work has been instrumental in developing new pharmaceutical solutions that enhance the efficacy and stability of therapeutic proteins.

Collaborations

He has collaborated with notable coworkers such as Martin John Corbett and Bosco S Wang, contributing to a dynamic research environment that fosters innovation.

Conclusion

Hong-Ming Shieh's contributions to the field of biochemistry through his patents and collaborations highlight his role as a significant inventor. His work continues to influence the development of stable pharmaceutical compositions, showcasing the importance of innovation in the medical field.