Company Filing History:
15 out of 270 
4 out of 250 
1 out of 1,035 
Years Active: 2014-2025
Title: The Innovative Contributions of Holly Kordasiewicz
Introduction: Holly Kordasiewicz is a renowned inventor based in San Diego, California, with an impressive portfolio of 20 patents. Her work primarily focuses on the development of compounds and methods aimed at addressing neurodegenerative diseases. Kordasiewicz has made significant strides in the fields of genetic modulation and therapeutic interventions.
Latest Patents: Among her latest inventions are several notable patents that showcase her expertise. One such patent is for "Compounds and methods for reducing ATXN3 expression." This invention provides compounds, methods, and pharmaceutical compositions that effectively reduce ATXN3 mRNA levels in cellular and animal models. By targeting this mRNA, Kordasiewicz's innovations aim to prevent or alleviate symptoms associated with neurodegenerative conditions, including ataxia, neuropathy, and aggregate formation, particularly in relation to SCA3.
In addition, her contributions extend to the "Modulation of huntingtin expression." This patent outlines methods and compositions designed to decrease huntingtin mRNA and protein levels in animals. The potential applications of this work include treatment or prevention of Huntington's disease and its related symptoms, showcasing her commitment to addressing critical neurological challenges.
Career Highlights: Kordasiewicz has had a noteworthy career working with leading biotechnology firms. Among her roles, she has contributed significantly to Ionis Pharmaceuticals, Inc. and Biogen MA Inc., where her research has evolved into practical applications for improving patient outcomes in neurodegenerative diseases.
Collaborations: Throughout her career, Kordasiewicz has collaborated with distinguished colleagues such as Susan M. Freier and Gene Hung. These collaborations have fostered an environment of innovation, allowing her to integrate diverse expertise into her research and inventions.
Conclusion: Holly Kordasiewicz is a pivotal figure in the realm of biomedical innovation, particularly within neurodegenerative disease research. Her patents reflect her dedication to discovering actionable solutions for complex medical challenges. With a strong foundation in collaboration and a clear focus on impactful inventions, Kordasiewicz continues to influence the field and inspire future advancements.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.