Company Filing History:
Years Active: 2000-2006
Title: Holger Zimmermann: Innovator in Hormone Replacement Therapy
Introduction
Holger Zimmermann is a notable inventor based in Ilmenau-Roda, Germany. He has made significant contributions to the field of hormone replacement therapy, holding a total of 3 patents. His work focuses on innovative methods for administering hormones, particularly for therapeutic purposes.
Latest Patents
One of Zimmermann's latest patents involves the use of biogenic estrogen sulfamates for hormone replacement therapy. This invention relates to the oral discontinuous application of these sulfamates, which can be administered in intervals ranging from 2 to 40 days. The invention also includes the additional application of gestagens, preferably in the form of an implant or an intrauterine releasing system (IUD). The biogenic estrogen sulfamates used in this invention include estrone sulfamate, estradiol sulfamate, or an N-acyl sulfamate of estrone, estradiol, or estriol, with up to 7 carbon atoms in the acyl chain.
Another significant patent by Zimmermann is a bioadhesive tablet containing testosterone and testosterone ester mixtures. This invention provides a method for producing a predetermined testosterone time-release profile, particularly beneficial for elderly men suffering from partial androgen deficiency. The process involves spray-drying an alcoholic solution or suspension of testosterone and at least one testosterone ester, combined with an organic polymer to form an active ingredient premix. The resulting bioadhesive tablet can be buccally administered to achieve a timed release profile of testosterone, which varies according to circadian rhythms.
Career Highlights
Throughout his career, Holger Zimmermann has worked with reputable companies such as Jenapharm GmbH & Co. KG and Schering Aktiengesellschaft. His experience in these organizations has contributed to his expertise in the field of hormone therapies and innovative drug delivery systems.
Collaborations
Zimmermann has collaborated with notable colleagues, including Michael Oettel and Michael Dittgen. These partnerships have likely enhanced his research and development efforts in the pharmaceutical industry.
Conclusion
Holger Zimmermann's contributions to hormone replacement therapy through his innovative patents demonstrate his commitment to improving healthcare solutions. His work continues to influence the field and offers promising advancements for patients in need of hormone therapies.