Holger Kraus

Title: Holger Kraus: Innovator in Medicinal Aerosol Formulations

Introduction

Holger Kraus is a notable inventor based in Rickenbach, Switzerland. He has made significant contributions to the field of medicinal aerosol formulations, holding two patents that enhance the delivery and stability of pharmaceutical compounds.

Latest Patents

Kraus's latest patents focus on innovative medicinal aerosol formulations. One patent describes a pressure-liquefied propellant mixture for aerosols, which includes dinitrogen monoxide and hydrofluoroalkanes. This formulation improves the wetting properties of pharmaceutically active compounds, addressing existing formulation challenges. The use of dinitrogen monoxide allows for specific control over pressure and particle size distribution, enhancing the storage stability of oxidation-sensitive active compounds. Additionally, the propellant mixture can include carbon dioxide if desired. Another patent involves the use of solid, pharmaceutically acceptable salts of cromoglycic acid and/or nedocromil as carriers in suspension aerosol formulations. This approach improves dispersion properties, increases the stability of moisture-sensitive active compounds, and allows for more accurate dosing, particularly for low-dose active compounds.

Career Highlights

Holger Kraus is associated with Jago Research AG, where he continues to innovate in the field of medicinal aerosols. His work has led to advancements that benefit both pharmaceutical companies and patients.

Collaborations

Kraus collaborates with notable colleagues, including Manfred Keller and Kurt Herzog, contributing to a dynamic research environment that fosters innovation.

Conclusion

Holger Kraus is a distinguished inventor whose work in medicinal aerosol formulations has the potential to significantly improve pharmaceutical delivery systems. His innovative patents reflect a commitment to enhancing the efficacy and stability of medicinal products.