Hiroshi Shiragami

This inventor holds 18 USPTO granted patents, primarily in Nucleoside Chemistry. Top assignees: Ajinomoto Co., Ltd., Ajinomoto Co., Inc., Patent & Licensing Department. Active years: 1989-2001.

IDiyas Innovation Intelligence. (2026). Inventor Profile: Hiroshi Shiragami. Retrieved from https://idiyas.com/inventor/hiroshi-shiragami

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

USPTO Granted Patents = 18

% Patents Active = 100.0

Average Co-Inventor Count = 3.8

ph-index = 5

Forward Citations = 81(Granted Patents)

Company Filing History:

Ajinomoto Co., Inc., Patent & Licensing Department

patent

Years Active: 1989-2001

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Areas of Expertise:

Nucleosides

Purine Derivatives

Acyclic Nucleosides

Dideoxynucleosides

Isomerization

Transglycosylation

Selective Hydrolysis

Purification Methods

Chemical Processes

Synthesis Techniques

Kawasaki, JP

18 patents (USPTO):Sort by Forward CitationsExplore Patents

1. 6306647 - Process for producing and purifying 2′,3′-dideoxynucleosides, and process for producing 2′,3′-dideoxy-2′,3′-didehydronucleosides (2001-10-23),

2. 6252075 - Process for producing purine derivatives (2001-06-26),

3. 6245910 - Process for producing purine derivatives (2001-06-12),

4. 6087497 - Process for producing purine derivatives (2000-07-11),

5. 5942617 - Process for producing purine derivatives (1999-08-24),

6. 5831092 - Process for producing purine derivatives (1998-11-03),

7. 5792868 - Process for producing acyclic nucleosides and process for separating (1998-08-11),

8. 5688948 - Process for isomerizing acyclic nucleosides and process for separating (1997-11-18),

9. 5633366 - Pyrimidine nucleoside derivatives and methods for producing them (1997-05-27),

10. 5625057 - Process for preparing 2',3'-Dideoxy-2',3'-dehydronucleosides (1997-04-29),

11. 5466793 - Process for preparing 2', 3'- dideoxyinosine (1995-11-14),

12. 5451671 - Method of purifying 2',3'-dideoxynucleosides (1995-09-19),

13. 5336770 - Transglycosilation process for producing acyclic nucleosides (1994-08-09),

14. 5310895 - Method for production of nucleoside derivatives by selective hydrolysis (1994-05-10),

15. 5290927 - Process for preparing 2',3'-dideoxyadenosine (1994-03-01),

Title: Hiroshi Shiragami: Innovator in Nucleoside Chemistry

Introduction

Hiroshi Shiragami is a prominent inventor based in Kawasaki, Japan. He has made significant contributions to the field of nucleoside chemistry, holding a total of 18 patents. His work has advanced the understanding and production of various nucleoside derivatives, which are crucial in pharmaceutical applications.

Latest Patents

Shiragami's latest patents include innovative processes for producing and purifying 2′,3′-dideoxynucleosides. He has developed a method for converting uridines to 2′,3′-dideoxy-2′,3′-didehydrouridines by reacting acetic anhydride with a 2′,3′-O-alkoxymethylideneuridine intermediate. Additionally, he has created a process for producing purine derivatives, specifically focusing on 7-benzylpurine derivatives. This involves reacting an acetylpurine nucleoside with a benzyl halide to benzylate the 7-position of the purine base, followed by hydrolysis of the glycoside bond.

Career Highlights

Throughout his career, Shiragami has worked with notable companies, including Ajinomoto Co., Ltd. and Ajinomoto Co., Inc., in their Patent & Licensing Department. His expertise in nucleoside chemistry has positioned him as a key figure in the development of new pharmaceutical compounds.

Collaborations

Shiragami has collaborated with esteemed colleagues such as Kunisuke Izawa and Keizo Yamashita. Their combined efforts have contributed to the advancement of nucleoside research and development.

Conclusion

Hiroshi Shiragami's innovative work in nucleoside chemistry and his extensive patent portfolio highlight his significant impact on the field. His contributions continue to influence pharmaceutical research and development, showcasing the importance of innovation in science.

Profile summary based on public USPTO records.

Data Sources: USPTO Patent Grant XML, Patent Center, EPO & CIPO • Normalized by IDiyas Innovation Graph. Methodology & provenance architecturePlease report any incorrect information to [email protected]