Location History:
- Kusatsu, JP (1993 - 1996)
- Shiga, JP (2013)
Company Filing History:
Years Active: 1993-2013
Title: Hiroshi Shikama: Innovator in Therapeutic Agents
Introduction
Hiroshi Shikama is a notable inventor based in Kusatsu, Japan. He has made significant contributions to the field of therapeutic agents, particularly in the treatment of septic shock and related conditions. With a total of 3 patents to his name, Shikama's work is recognized for its potential impact on medical treatments.
Latest Patents
One of Shikama's latest patents is focused on an anti-shock agent comprising a diaminotrifluoromethylpyridine derivative. This invention addresses the critical issue of septic shock, which can lead to systematic inflammatory reaction syndrome and multiple organ failure (MOF). The therapeutic agent aims to suppress the infiltration of inflammatory cells, which play a key role in the progression of MOF. The active ingredient is represented by a specific formula, where X can be a cycloalkylcarbonyl group, an alkenylcarbonyl group, a thiophenecarbonyl group, or a benzoyl group, and Y is an alkylsulfonyl group.
Another significant patent involves muteins of tumor necrosis factor (TNF) pharmaceutical compositions. This invention includes a polypeptide with a defined amino acid sequence and its mutein, which replaces part of the sequence with an amino acid sequence containing Arg-Gly-Asp. The patent also covers a recombinant plasmid containing DNA encoding the polypeptide, a transformed microbial cell, and a process for producing the polypeptide.
Career Highlights
Hiroshi Shikama is currently associated with Ishihara Sangyo Kaisha, Ltd., where he continues to innovate in the field of pharmaceuticals. His work has the potential to lead to significant advancements in medical treatments, particularly for conditions that currently have limited therapeutic options.
Collaborations
Shikama has collaborated with notable coworkers, including Nobutoshi Yamada and Masanari Kato. Their combined expertise contributes to the development of innovative solutions in the pharmaceutical industry.
Conclusion
Hiroshi Shikama's contributions to the field of therapeutic agents highlight his role as a key innovator in medical science. His patents reflect a commitment to addressing critical health challenges, and his work continues to inspire advancements in treatment options.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.