Company Filing History:
4 out of 416 
3 out of 27 
1 out of 26 
Years Active: 1983-2021
Title: Hiroshi Morikawa: Innovator in Pharmaceutical Chemistry
Introduction
Hiroshi Morikawa is a distinguished inventor based in Tokyo, Japan. He has made significant contributions to the field of pharmaceutical chemistry, particularly in the development of compounds aimed at treating nocturia. With a total of six patents to his name, Morikawa's work has the potential to impact the lives of many individuals suffering from this condition.
Latest Patents
One of Morikawa's latest patents focuses on a pyridine derivative designed for pharmaceutical compositions targeting nocturia. The invention addresses the need for a compound that can effectively inhibit the nocturnal activity of placental leucine aminopeptidase (P-LAP). By maintaining or increasing endogenous arginine vasopressin (AVP) levels, the compound enhances the antidiuretic effect, thereby reducing the frequency of nocturnal voids. The research has demonstrated that (2R)-3-amino-2-{[4-(substituted pyridine)-2-yl]methyl}-2-hydroxy-propanoic acid derivatives exhibit excellent P-LAP inhibitory activity. In studies conducted on water-loaded rats, these compounds were found to increase endogenous AVP levels and consequently reduce urine production. This innovative approach offers a promising avenue for treating nocturia through P-LAP inhibition.
Career Highlights
Throughout his career, Morikawa has worked with notable companies in the pharmaceutical industry, including Astellas Pharma GmbH and Kotobuki Pharmaceutical Co. Ltd. His experience in these organizations has allowed him to refine his expertise in drug development and innovation.
Collaborations
Morikawa has collaborated with esteemed colleagues such as Kenichi Kawaguchi and Akihiro Ishihata. These partnerships have contributed to the advancement of his research and the successful development of his patented compounds.
Conclusion
Hiroshi Morikawa's contributions to pharmaceutical chemistry, particularly in the treatment of nocturia, highlight his innovative spirit and dedication to improving patient care. His work continues to pave the way for new therapeutic options in the field.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.