Company Filing History:
Years Active: 1987-1989
Title: Innovations by Hidetsune Tamaoki
Introduction
Hidetsune Tamaoki is a notable inventor based in Hiromachi, Japan. He has made significant contributions to the field of pharmaceuticals, particularly in the development of enkephalinase B inhibitors. With a total of 2 patents, his work has implications for enhancing enkephalin activity in vivo.
Latest Patents
Tamaoki's latest patents include the development of enkephalinase B inhibitors, specifically Propioxatins A and B. These compounds can be prepared by cultivating a suitable strain of Kitasatosporia, such as Kitasatosporia sp. SANK 60684 (FERM-P 7581). The compounds are capable of being salified to produce pharmaceutically acceptable salts. Additionally, he has worked on the preparation of peptides with C-terminal proline amide. This process involves reacting a protein substrate with carboxypeptidase Y in the presence of ammonia, which is generated through the aqueous reaction of an ammonium salt and an alkali. An example of the peptide product is human calcitonin.
Career Highlights
Tamaoki is associated with Sankyo Company, Limited, where he has been able to apply his innovative ideas in a practical setting. His work has contributed to advancements in pharmaceutical research and development.
Collaborations
Some of his notable coworkers include Yoshinori Inaoka and Shuji Takahashi, who have collaborated with him on various projects.
Conclusion
Hidetsune Tamaoki's contributions to the field of pharmaceuticals through his patents and collaborations highlight his role as an influential inventor. His work continues to impact the development of new therapeutic agents.