Company Filing History:
Years Active: 2020-2024
Title: Hidetaka Suga: Innovator in Stem Cell Research
Introduction
Hidetaka Suga is a prominent inventor based in Wako, Japan, known for his significant contributions to the field of stem cell research. He holds a total of four patents that focus on innovative methods for producing adenohypophysis and precursor tissues from human pluripotent stem cells. His work has the potential to advance medical science and therapeutic applications.
Latest Patents
One of Hidetaka Suga's latest patents is a method for producing adenohypophysis or precursor tissue. This invention provides a technique for inducing adenohypophysis or precursor tissue in vitro from human pluripotent stem cells. The method involves culturing an aggregate of human pluripotent stem cells in suspension within a medium that contains a bone morphogenetic protein signal transduction pathway activating substance and a substance that acts on the Shh signal pathway. This process results in a human cell aggregate that contains hypothalamus neuroepithelial tissue and surface ectoderm. Further culturing of this aggregate leads to the formation of hypophysial placode and/or Rathke's pouch, ultimately yielding a human cell aggregate with both hypothalamus neuroepithelial tissue and hypophysial placode or Rathke's pouch.
Another notable patent by Suga is a method for producing hypophysis precursor tissue. This invention outlines a process for obtaining aggregates that contain rostral hypothalamus tissue, rostral head ectodermal tissue, hypophysis precursor tissue, and hypophysis hormone-producing cells. The method utilizes a serum-free medium, preferably free of growth factors and insulins, to form homogeneous aggregates of stem cells from pluripotent stem cells, which are then subjected to floating-culture.
Career Highlights
Hidetaka Suga has worked with notable organizations such as RIKEN Corporation and Sumitomo Chemical Company, Limited. His experience in these companies has contributed to his expertise in stem cell research and innovation.
Collaborations
Throughout his career, Suga has collaborated with esteemed colleagues, including Yoshiki Sasai and Chikafumi Ozone. These collaborations have further enriched his research and development efforts in the field.
Conclusion
Hidetaka Suga is a distinguished inventor whose work in stem cell research has led to groundbreaking patents that may
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