Herwald Klein

Title: Herwald Klein: Innovator in Immunoglobulin-G Preparation

Introduction

Herwald Klein is a notable inventor based in Weiterstadt, Germany. He has made significant contributions to the field of immunology through his innovative work in the preparation of intravenous tolerable immunoglobulin-G. His research focuses on developing methods that enhance the safety and efficacy of immunoglobulin treatments for patients, particularly those who are immunosuppressed.

Latest Patents

Herwald Klein holds a patent for a method of manufacturing an intravenously tolerable immunoglobulin-G preparation. This method ensures that the preparation is free of aggregates, vasoactive substances, and proteolytic enzymes, making it suitable for all types of patients. The process involves treating a starting material that contains immunoglobulin G, from which coagulation factors have been removed, with 0.4 to 1.5% by volume of octanoic acid. The treated material is then chromatographed, particularly on an ion or cation exchanger or hydrophobic matrix. This innovative approach has the potential to improve patient outcomes significantly.

Career Highlights

Herwald Klein is associated with Biotest Pharma GmbH, where he has been instrumental in advancing research and development in immunoglobulin therapies. His work has not only contributed to the scientific community but has also paved the way for new treatment options for patients with compromised immune systems.

Collaborations

Throughout his career, Klein has collaborated with esteemed colleagues such as Norbert Kothe and Dieter Rudnick. These partnerships have fostered a collaborative environment that encourages innovation and the sharing of ideas in the field of immunology.

Conclusion

Herwald Klein's contributions to the development of intravenous tolerable immunoglobulin-G preparations highlight his dedication to improving patient care. His innovative methods and collaborative efforts continue to influence the field of immunology positively.