Herman J Eichel, Deceased

Title: Herman J. Eichel: Inventor of Delayed-Release Pharmaceutical Preparations

Introduction

Herman J. Eichel was an inventor associated with Columbus, Ohio, and Kinaform Technology, Inc. His patent work focused on pharmaceutical preparations designed to delay and sustain the release of water-soluble drugs. Eichel is credited with 2 patents in the information provided.

Latest Patents

Eichel’s listed patents describe related approaches to controlling when a drug is released after administration. Both use a hydratable diffusion barrier around a water-soluble drug core, designed to delay release for approximately two to ten hours. The barrier combines a film-forming polymer with additives that regulate hydration and permeability.

The patent for a delayed, sustained-release diltiazem preparation describes coating drug granules to form microparticles. Different barrier thicknesses create components with longer and shorter release delays, allowing the preparation to provide a staged release profile.

The delayed, sustained-release propranolol preparation uses a similar barrier-based design. Its coated microparticles may also be combined with an immediate-release drug, bringing delayed and immediate release components together in one preparation.

Career Highlights

Eichel’s listed inventions address a practical pharmaceutical challenge: controlling the timing of drug release. The described formulations use polymer coatings and selected additives to adjust how quickly water reaches the drug core and how the drug passes through the barrier.

Collaborations

The supplied information identifies Brent D. Massmann and Joseph E. Cobb, Jr. as Eichel’s coworkers. It does not specify their roles in the development of the listed inventions.

Conclusion

Herman J. Eichel’s two listed patents center on polymer-based diffusion barriers for delayed and sustained drug release, with applications described for diltiazem and propranolol.