Heping Zhang

Title: Heping Zhang: Innovator in Biflavanoid Synthesis

Introduction

Heping Zhang is a notable inventor based in Elmhurst, Illinois, who has made significant contributions to the field of organic chemistry. His work primarily focuses on the synthesis of biflavanoids, which are compounds known for their potential health benefits and applications in various industries.

Latest Patents

Heping Zhang holds a patent for "Robustaflavone, intermediates and analogues and method for preparation thereof." This patent outlines a method for synthesizing robustaflavone and its intermediates, which involves constructing apigenin ethers with specific functionalities. The innovative method utilizes transition metal catalysis for cross-coupling and includes a regioselective iodination process. The formation of an apigenin 3′-boronate through a palladium-catalyzed exchange is also a key aspect of this synthesis. Ultimately, the Suzuki coupling technique allows for the creation of the sterically congested 6-3′′ biaryl bond, providing access to the desired biflavanoid system.

Career Highlights

Heping Zhang is associated with Advanced Life Sciences, Inc., where he continues to advance his research in the synthesis of complex organic compounds. His work has the potential to lead to the development of analogues of other biflavanoids, such as hinokifavone, rhusflavone, and succedaneaflavone.

Collaborations

Heping Zhang has collaborated with notable colleagues, including David E. Zembower and Michael T. Flavin. These collaborations have likely contributed to the innovative approaches and methodologies in his research.

Conclusion

Heping Zhang's contributions to the field of organic chemistry, particularly in the synthesis of biflavanoids, highlight his role as an influential inventor. His patented methods and ongoing research continue to pave the way for advancements in this important area of study.