Company Filing History:
Years Active: 2004-2006
Title: Henry William Bosch: Innovator in Pharmaceutical Milling Technology
Introduction
Henry William Bosch is a notable inventor based in Bryn Mawr, PA (US). He has made significant contributions to the field of pharmaceutical milling technology. With a total of 2 patents, Bosch has developed innovative methods that enhance the efficiency and effectiveness of milling processes.
Latest Patents
Bosch's latest patents focus on a small-scale or micro media-mill designed for milling materials, particularly pharmaceutical products. The method utilizes a dispersion containing attrition milling media and the product to be milled. The milling media can be polymeric, specifically formed of polystyrene or cross-linked polystyrene, with a nominal diameter of no greater than 500 microns. Other sizes include 200 microns and 50 microns, as well as a mixture of these sizes. The mill features a relatively small vessel equipped with an opening, an agitator, a coupling, and a motor. The agitator includes a rotor and a shaft extending from it, with the rotor being cylindrical or having other configurations, including tapered end surfaces. The coupling can either close the vessel opening or attach to the motor to seal the opening. A sealing mechanism, such as mechanical or lip seals, allows the rotor shaft to rotate while maintaining the integrity of the vessel. The design also incorporates one or more ports for circulating the dispersion, enabling milling to occur in batches or through recirculation within the milling chamber. The rotor is dimensioned to maintain a small gap from the inner surface of the vessel, and the system includes a method for cooling the dispersion.
Career Highlights
Henry William Bosch is currently associated with Elan Pharma International Limited, where he applies his expertise in pharmaceutical technology. His work has significantly impacted the efficiency of milling processes in the industry.
Collaborations
Bosch has collaborated with notable colleagues, including Robert G Reed and David A Czekai, contributing to advancements in their field.
Conclusion
Henry William Bosch's innovative work in pharmaceutical milling technology showcases his commitment to enhancing industry practices. His patents reflect a deep understanding of the complexities involved in milling processes, making him a valuable contributor to the field.