This inventor holds 3 USPTO granted patents. Top assignees: Johns Hopkins University, Bios Corporation. Active years: 1980-1988.
Company Filing History:
Years Active: 1980-1988
Title: The Innovative Contributions of Henry N Wagner
Introduction
Henry N Wagner is a notable inventor based in Baltimore, MD (US), recognized for his significant contributions to the field of neuroreceptor activity assessment. With a total of 3 patents, Wagner has developed innovative methods to monitor the effectiveness of drugs and substances that affect brain chemistry.
Latest Patents
Wagner's latest patent focuses on neuroreceptor activity assessment. This invention allows for the efficient and relatively inexpensive monitoring of the effectiveness of drugs that impact brain chemistry. The process involves administering radioactive tracer substances that bind to presynaptic or postsynaptic neuroreceptors in a patient. The emissions, primarily positrons and gamma rays emitted from the positrons, are measured to indicate the number and degree of occupancy or blocking of the neuroreceptors. A mathematical model is utilized to calculate these values, which are then compared with intra-person or inter-person controls to determine the degree of drug response. This method is particularly applicable in treating conditions such as Parkinson's disease, schizophrenia, and drug addictions. The apparatus used is simple, including a patient head support and gamma ray directional detectors, connected to circuitry for accurate measurements.
Career Highlights
Throughout his career, Wagner has worked with prestigious institutions, including Johns Hopkins University and Bios Corporation. His work has significantly advanced the understanding of neuroreceptor activity and its implications for drug treatment.
Collaborations
Wagner has collaborated with notable individuals in his field, including Robert H Wake, enhancing the impact of his research and inventions.
Conclusion
Henry N Wagner's innovative work in neuroreceptor activity assessment has made a lasting impact on the medical field, particularly in the treatment of neurological disorders. His contributions continue to influence the development of effective therapeutic strategies.