Henry E Blair

Title: The Innovations of Henry E. Blair

Introduction

Henry E. Blair is a notable inventor based in Barnstable, MA (US). He has made significant contributions to the field of biochemistry, particularly in the development of assays for measuring enzyme activity. With a total of 6 patents to his name, Blair's work has had a lasting impact on diagnostic methods.

Latest Patents

One of his latest patents is the "Alpha amylase assay," which details a method for measuring the amount of α-amylase in a liquid sample. This innovative method involves providing an oligosaccharide substrate characterized by containing at least three glucose units. The reducing-end glucose unit is bonded to a label that exhibits an optically measurable change upon cleavage of the bond. The terminal glucose unit is bonded to a blocking substituent that inhibits cleavage by exo-enzymes. The process includes contacting the sample with the oligosaccharide substrate and a first exo-enzyme capable of cleaving the bond between the reducing-end glucose unit and the label, followed by measuring the optically measurable change as an indicator of α-amylase in the sample.

Career Highlights

Throughout his career, Henry E. Blair has worked with prominent organizations, including Genzyme Corporation. His expertise in biochemistry and assay development has positioned him as a valuable contributor to the field.

Collaborations

Blair has collaborated with notable individuals such as Stanley E. Charm and Richard P. Crowley. These partnerships have further enhanced his innovative work and contributed to the success of his projects.

Conclusion

Henry E. Blair's contributions to the field of biochemistry through his patents and collaborations highlight his role as a significant inventor. His work continues to influence diagnostic methods and enzyme measurement techniques.