Company Filing History:
Years Active: 2022
Title: Innovations by Inventor Henrik H J Persson in Proximity Ligation Assays
Introduction: Henrik H J Persson is an accomplished inventor based in Palo Alto, California. He holds a patent for his innovative work in the field of molecular biology, specifically focused on enhancing the specificity of ligation assays. This advancement is significant for both research and clinical applications.
Latest Patents: Persson's notable patent is titled "Highly Specific Circular Proximity Ligation Assay." This invention utilizes proximity-probes as bridges to connect two free oligonucleotides through a dual ligation event, resulting in the formation of a circle. This innovative approach allows for the quantification of these circles through methods such as qPCR. The inclusion of an extra oligonucleotide is designed to improve specificity by decreasing random background ligation events. Moreover, this circular formation offers unique advantages since uncircularized DNA can be eliminated with a straightforward exonuclease treatment, thus streamlining the workflow by eliminating the need for preamplification prior to qPCR.
Career Highlights: Henrik H J Persson works at Leland Stanford Junior University, where he contributes to cutting-edge research in molecular biology. His pioneering patent exemplifies his commitment to advancing scientific techniques and enhancing the reliability of diagnostic assays.
Collaborations: Throughout his career, Persson has collaborated with notable colleagues such as Roxana Jalili and Joseph L Horecka. These partnerships foster a dynamic research environment, promoting innovative thinking and problem-solving.
Conclusion: Henrik H J Persson's contributions to the field of molecular biology through his patent on highly specific circular proximity ligation assays highlight the importance of innovation in scientific research. His work not only enhances laboratory workflows but also holds the potential for significant impacts in clinical diagnostics. As the landscape of molecular biology continues to evolve, inventors like Persson will be vital in paving the way for future advancements.