This inventor holds 4 USPTO granted patents. Top assignees: Cambridge Antibody Technology Limited, Medical Research Council, Basf Aktiengesellschaft. Active years: 1996-2000.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Location History:
- Cambridge, GB (1996 - 1999)
- Hasselt, BE (1998 - 2000)
Company Filing History:
3 out of 28 
3 out of 259 
1 out of 10,816 
Years Active: 1996-2000
Title: The Innovations of Hendricus Renerus Hoogenboom
Introduction
Hendricus Renerus Hoogenboom is a notable inventor based in Hasselt, Belgium. He has made significant contributions to the field of biotechnology, particularly in the development of human antibodies. With a total of 4 patents to his name, Hoogenboom's work has had a profound impact on medical research and therapeutic applications.
Latest Patents
One of Hoogenboom's latest patents involves the creation of human antibodies that bind to human tumor necrosis factor alpha (hTNF.alpha.). These antibodies are characterized by their high affinity for hTNF.alpha., with a dissociation constant (K.sub.d) of <10.sup.-8 M or less. They also exhibit a slow off rate for hTNF.alpha. dissociation, making them effective in neutralizing hTNF.alpha. activity both in vitro and in vivo. The invention encompasses full-length antibodies as well as antigen-binding portions, which are useful for detecting hTNF.alpha. and inhibiting its activity in patients suffering from related disorders. Additionally, the patent includes nucleic acids, vectors, and host cells for expressing these recombinant human antibodies, along with methods for their synthesis.
Career Highlights
Throughout his career, Hoogenboom has worked with prestigious organizations, including the Medical Research Council and Cambridge Antibody Technology Limited. His innovative research has contributed to advancements in therapeutic antibodies, enhancing treatment options for various diseases.
Collaborations
Hoogenboom has collaborated with esteemed colleagues in the field, including Gregory Paul Winter and Andrew David Griffiths. These partnerships have fostered a collaborative environment that has led to groundbreaking discoveries in antibody technology.
Conclusion
Hendricus Renerus Hoogenboom's contributions to biotechnology and antibody development have established him as a prominent figure in the field. His innovative patents and collaborations continue to influence medical research and therapeutic advancements.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile