Location History:
- Ginsheim-Gustavsburg, DE (2008 - 2017)
- Russelsheim, DE (2020)
- Rüsselsheim, DE (2022)
Company Filing History:
6 out of 45 
2 out of 14 
1 out of 832,718 Years Active: 2008-2022
Title: The Innovative Contributions of Helmut Jonuleit
Introduction
Helmut Jonuleit is a distinguished inventor based in Ginsheim-Gustavsburg, Germany, known for his significant contributions to the field of immunology. With a remarkable portfolio of nine patents, Jonuleit's work focuses primarily on the detection and treatment of autoimmune diseases.
Latest Patents
Among his latest inventions is a pioneering in-vitro method for detecting autoimmune diseases or conditions. This method addresses the impaired responsiveness of CD4+ T-cells to regulatory T-cells, known as Treg resistance. By measuring the expression levels of peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPARGC1A or PGC-1α) in activated CD4+ T-cells from patients suffering from relapsing remitting multiple sclerosis, he aims to generate functional gene expression profiles for effective screening.
Another significant patent involves a screening methodology for identifying agents that can activate CD4+CD25+ regulatory T-cells. This method utilizes interactions with the HIV-1 GP120 binding site on CD4, which holds promise for the treatment of various autoimmune conditions, allergies, asthma, graft rejection, and tolerance induction.
Career Highlights
Throughout his career, Jonuleit has worked with several renowned companies, including Biotest AG and Universitätsmedizin der Johannes Gutenberg-Universität Mainz. His experience at these institutions has not only solidified his expertise but also facilitated groundbreaking research in the area of autoimmune diseases.
Collaborations
Jonuleit has collaborated with prominent figures in the research community, including John Wijdenes and Franz-Josef Schneider. These collaborations have greatly enriched his work and contributed to the advancement of innovative solutions for pressing medical challenges.
Conclusion
Helmut Jonuleit's inventive spirit and dedication to advancing medical science make him a noteworthy figure in the realm of innovation. His latest patents illustrate the potential for new diagnostic and therapeutic approaches in the treatment of autoimmune diseases, showcasing the vital role of inventors in shaping the future of healthcare.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.