Lynge, Denmark

Helle Fabricius Woldike

USPTO Granted Patents = 8 


Average Co-Inventor Count = 2.6

ph-index = 7

Forward Citations = 301(Granted Patents)


Location History:

  • Lynge, DK (1993 - 1999)
  • Bagsvaerd, DK (1999)

Company Filing History:


Years Active: 1993-1999

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8 patents (USPTO):Explore Patents

Title: Helle Fabricius Woldike: Innovator in Protein Production

Introduction

Helle Fabricius Woldike is a prominent inventor based in Lynge, Denmark. He has made significant contributions to the field of biotechnology, particularly in the production of proteins using filamentous fungi. With a total of 8 patents to his name, Woldike's work has paved the way for advancements in industrial protein production.

Latest Patents

Woldike's latest patents include innovative methods for producing Humicola lipases in Aspergillus. This process involves transforming Aspergillus oryzae with a vector system that contains DNA sequences for gene expression, a selection marker for transformants, and a sequence encoding the desired protein product. This method enables the industrial production of various polypeptides and proteins, including chymosin, proteases, lipases, and amylases. Additionally, he has developed a process for producing trypsin (trypsinogen) in filamentous fungi, which involves transforming the fungus with a vector that encodes protrypsin fused to a signal peptide.

Career Highlights

Woldike is currently associated with Novo Nordisk A/S, a leading global healthcare company. His work at Novo Nordisk has focused on enhancing the efficiency of protein production processes, contributing to the company's reputation for innovation in biotechnology.

Collaborations

Throughout his career, Woldike has collaborated with notable colleagues, including Fred Hagen and Carsten Mailand Hjort. These collaborations have further enriched his research and development efforts in the field of protein production.

Conclusion

Helle Fabricius Woldike is a distinguished inventor whose work in protein production has had a significant impact on biotechnology. His innovative methods and collaborations continue to drive advancements in the industry.

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