This inventor holds 1 USPTO granted patent and 1 published patent application. Top assignee: The University of British Columbia. Active years: 1996.
Company Filing History:
Years Active: 1996
Title: Helene C Cote: Innovator in Recombinant Polypeptides
Introduction
Helene C Cote is a distinguished inventor based in Vancouver, Canada. She has made significant contributions to the field of biochemistry, particularly in the development of recombinant polypeptides. Her innovative work has implications for coagulation and anticoagulation therapies.
Latest Patents
Helene C Cote holds a patent for "Stable recombinant meizothrombin-like polypeptides." This invention involves an isolated polynucleotide that encodes human prothrombin, modified to include amino acid substitutions at specific positions. The polypeptide produced is resistant to cleavage by thrombin and factor Xa, demonstrating reduced procoagulant activity while maintaining anticoagulant properties. This innovation has the potential to enhance therapeutic strategies in coagulation management.
Career Highlights
Cote is affiliated with the University of British Columbia, where she continues her research and development efforts. Her work has garnered attention for its potential applications in medical science, particularly in improving patient outcomes in coagulation disorders.
Collaborations
Throughout her career, Cote has collaborated with notable colleagues, including Ross T MacGillivray and Michael E Nesheim. These partnerships have contributed to the advancement of her research and the successful development of her patented technologies.
Conclusion
Helene C Cote's innovative contributions to the field of recombinant polypeptides highlight her role as a leading inventor in biochemistry. Her work not only advances scientific knowledge but also holds promise for future medical applications.