Location History:
- Shelter Island, NJ (US) (1999)
- Shelter Island, NY (US) (1997 - 2002)
- New York, NY (US) (1983 - 2015)
Company Filing History:
15 out of 67 
7 out of 712 
2 out of 55 
Years Active: 1983-2015
Title: Innovation and Impact: The Patents and Career of Helen Vlassara
Introduction
Helen Vlassara, based in Shelter Island, NY, is a renowned inventor with a remarkable portfolio of 25 patents. Her work primarily focuses on innovative therapies for lysosomal disorders, showcasing her commitment to advancing medical research and treatment options.
Latest Patents
Among her latest patents is the invention titled "Anti-TNF-α therapy for the mucopolysaccharidoses and other lysosomal disorders." This innovative method involves administering an agent for enzyme replacement therapy combined with anti-TNF-α therapy to treat subjects with lysosomal disorders effectively. Additionally, her patent on the "Inhibition of TNF-α induced activation of NFKB by pentosan polysulfate" highlights the therapeutic potential of oral pentosan polysulfate (PPS) compositions in treating diseases such as diabetes, inflammation, and atherosclerosis while effectively reducing matrix metalloproteinases (MMPs).
Career Highlights
Helen has significantly contributed to the field of medical research through her tenure at prestigious institutions. She has worked with The Picower Institute for Medical Research and The Rockefeller University, where she collaborated on groundbreaking research projects. Her expertise in lysosomal disorders has solidified her reputation as a leading figure in the medical innovation landscape.
Collaborations
Throughout her career, Helen Vlassara has collaborated with notable figures in the medical research community. Notable coworkers include Anthony Cerami and Richard J. Bucala, both of whom have made significant contributions to advancements in biological science and therapeutics.
Conclusion
Helen Vlassara's extensive patent portfolio and her impactful career in medical research underscore her dedication to innovation. Her work not only opens new avenues for therapy in lysosomal disorders but also exemplifies the critical role of inventors in driving advancements within the healthcare field.