The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 13, 2015
Filed:
Jun. 20, 2012
Edward H. Schuchman, Haworth, NJ (US);
Calogera M. Simonaro, Haworth, NJ (US);
Gary E. Striker, New York, NY (US);
Helen Vlassara, New York, NY (US);
Edward H. Schuchman, Haworth, NJ (US);
Calogera M. Simonaro, Haworth, NJ (US);
Gary E. Striker, New York, NY (US);
Helen Vlassara, New York, NY (US);
Icahn School of Medicine at Mount Sinai, New York, NY (US);
Abstract
The present invention relates to methods of treating a subject with a lysosomal disorder, by administering an agent for enzyme replacement therapy and an agent for anti-TNF-α therapy; by administering a pentosan polysulfate therapy; or by administering a substrate reduction therapy and an anti-TNF-α therapy. The invention further relates to a method of reducing inflammatory cytokines in a subject with a lysosomal disorder that is being treated by enzyme replacement therapy, by administering an agent for anti-TNF-α therapy.