Location History:
- Stockholm, SE (2016 - 2019)
- Kista, SE (2022)
Company Filing History:
1 out of 1 
2 out of 832,843 Years Active: 2016-2022
Title: Innovations by Helen Bergquist
Introduction
Helen Bergquist is a notable inventor based in Stockholm, Sweden. She has made significant contributions to the field of biotechnology, particularly in the development of therapeutic methods for genetic disorders. With a total of 3 patents to her name, her work focuses on innovative solutions for complex medical conditions.
Latest Patents
Bergquist's latest patents include a therapeutic method for Huntington's disease. This invention involves anti-gene oligonucleotides designed to hybridize with DNA in the HTT gene. These oligonucleotides are based on locked nucleic acids and phosphorodiamidate morpholino oligomers. They target sequences where the majority of repeats are CAG/CTG, aiming to downregulate the expression of the HTT gene. This results in reduced HTT mRNA and protein levels in affected individuals, contributing to the diagnosis, treatment, and prevention of Huntington's disease.
Another significant patent addresses the diagnosis and treatment of Friedreich's ataxia. This invention utilizes oligonucleotides based on peptide nucleic acid or equivalent analogs. These oligonucleotides are designed to dissociate higher-order structures in DNA associated with Friedreich's ataxia. The method aims to improve diagnosis and treatment options for this genetic disorder.
Career Highlights
Throughout her career, Helen Bergquist has worked with various companies, including Rula Zain-Luqman. Her innovative approaches and dedication to research have positioned her as a key figure in her field.
Collaborations
Bergquist has collaborated with notable individuals such as Rula Zain-Luqman and Liam Good. These partnerships have further enhanced her research and development efforts.
Conclusion
Helen Bergquist's contributions to biotechnology and her innovative patents demonstrate her commitment to advancing medical science. Her work continues to impact the diagnosis and treatment of genetic disorders, showcasing the importance of innovation in healthcare.