Beringen, Switzerland

Heinrich Bollinger


Average Co-Inventor Count = 2.9

ph-index = 1

Forward Citations = 4(Granted Patents)


Company Filing History:


Years Active: 1985-2005

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6 patents (USPTO):Explore Patents

Title: **Innovative Works of Heinrich Bollinger**

Introduction

Heinrich Bollinger, an accomplished inventor based in Beringen, Switzerland, holds an impressive portfolio of six patents. His work predominantly focuses on the synthesis of novel chemical compounds, specifically within the realm of hypoxanthine derivatives. Bollinger’s innovative contributions have the potential to influence various fields, particularly in pharmaceuticals and medicinal chemistry.

Latest Patents

One of Heinrich Bollinger's latest patents outlines a sophisticated method for synthesizing 9-substituted hypoxanthine derivatives. This improved method includes a series of intricate steps:

1. Reacting aminocyanacetamide with triethyl orthoformate to create an imidoester derivative.

2. Forming a compound with a reactive amino group on a hydrocarbyl moiety linked via an amide group to a physiologically active moiety.

3. Reacting the imidoester with the aforementioned compound to yield a derivative of aminoimidazole-4-carboxamide.

4. Developing the heterocyclic ring of the purine moiety by reacting it with triethyl orthoformate, resultant in a 9-substituted hypoxanthine compound.

5. Hydrolyzing any present ester of the optionally esterified benzoyl group.

Another significant patent focuses on the crystal forms of 9-substituted hypoxanthine derivatives, specifically the bifunctional compound N-4-carboxyphenyl-3-(6-oxohydropurin-9-yl) propanamide monopotassium salt. This compound appears in various crystal forms, with the most stable being designated as Type I, a monopotassium salt monohydrate.

Career Highlights

Throughout his career, Heinrich Bollinger has been associated with notable organizations such as Eprova AG and Merck. His role in these companies enables him to engage in cutting-edge research and development, further advancing his innovative projects. His significant contributions have established him as a noteworthy figure in his industry.

Collaborations

Heinrich Bollinger's professional journey includes collaborations with esteemed colleagues such as Alvin Jerald Glasky and Hans Rudolf Müller. These partnerships have likely enriched his work, promoting a shared exchange of ideas and advancements in their respective fields of expertise.

Conclusion

Heinrich Bollinger's dedication to innovation is evident through his patents and collaborative efforts. His work in synthesizing 9-substituted hypoxanthine derivatives showcases the potential impact such research can have on pharmaceuticals. As he continues to develop his ideas and innovate, Bollinger is poised to make further significant contributions to the scientific community.

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