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1 out of 3 Years Active: 2010-2014
Title: Hechmi Louzir: Innovator in Leishmaniasis Research
Introduction
Hechmi Louzir is a prominent inventor based in La Marsa, Tunisia. He has made significant contributions to the field of combating leishmaniases, with a total of four patents to his name. His work focuses on understanding the virulence of the Leishmania parasite and developing innovative therapeutic solutions.
Latest Patents
One of Louzir's latest patents involves genes associated with Leishmania parasite virulence. This invention pertains to the isolation of a protein-coding gene known as LmPDI, which has two regions identical to the sequence (Cys-Gly-His-Cys) of the potential active site of protein disulphide isomerase (PDI). The LmPDI protein is predominantly expressed in the most virulent isolates of the parasite, making it a novel therapeutic target for developing anti-leishmaniasis medicaments. Another significant patent is an immunogenic composition that includes an antigenic polypeptide consisting of a fragment of the protein histone H2B, specifically the N-terminal region, along with an adjuvant that stimulates the immune response.
Career Highlights
Hechmi Louzir has worked with esteemed institutions such as the Institut Pasteur de Tunis and the Institut Pasteur. His research has been pivotal in advancing the understanding of leishmaniasis and developing potential treatments.
Collaborations
Louzir has collaborated with notable colleagues, including Mehdi Chenik and Koussay Dellagi, contributing to the collective effort in leishmaniasis research.
Conclusion
Hechmi Louzir's innovative work in the field of leishmaniasis has the potential to lead to significant advancements in treatment options. His contributions are vital in the ongoing battle against this parasitic disease.