This inventor holds 2 USPTO granted patents. Top assignees: Betagene, Inc., The University of Texas System. Active years: 1998-1999.
Location History:
- Arlington, TX (US) (1998)
- Dallas, TX (US) (1999)
Company Filing History:
2 out of 4 
2 out of 5,630 
Years Active: 1998-1999
Title: He-Ping Han: Innovator in Hexokinase Inhibition
Introduction
He-Ping Han is a notable inventor based in Arlington, TX (US), recognized for his contributions to the field of biochemistry, particularly in the inhibition of hexokinase enzymes. With a total of 2 patents, his work has significant implications for mammalian cell biology and metabolic regulation.
Latest Patents
He-Ping Han's latest patents focus on methods and compositions for inhibiting hexokinase. These patents disclose various compositions and methods aimed at inhibiting hexokinase enzymes in mammalian cells. Specifically, they provide proteins that stimulate the production of trehalose-6-phosphate and their respective genes. The patents also include hexokinase-specific ribozymes and genes encoding such constructs. Additionally, they describe agents that competitively reduce hexokinase activity by displacing hexokinase from mitochondria, along with their respective genes. This group of agents includes inactive hexokinases and fragments that retain mitochondrial binding functions, as well as hexokinase-glucokinase chimeras that substitute glucokinase activity for hexokinase activity. The patents further detail mammalian cells that incorporate these hexokinase inhibitors, methods for creating such cells, and various in vitro and in vivo applications of cells with reduced hexokinase activity.
Career Highlights
He-Ping Han has worked with prominent organizations, including the University of Texas System and Betagene, Inc. His career reflects a commitment to advancing scientific knowledge and practical applications in the field of metabolic research.
Collaborations
Throughout his career, He-Ping Han has collaborated with esteemed colleagues such as Christopher B. Newgard and Karl D. Normington. These collaborations have contributed to the depth and impact of his research.
Conclusion
He-Ping Han's innovative work in hexokinase inhibition showcases his significant contributions to biochemistry and cellular biology. His patents and collaborations highlight the importance of his research in understanding and manipulating metabolic pathways.