Harvey C Tian

Title: Harvey C Tian: Revolutionizing Single Cell Genomic Analysis Through Microfluidic Devices

Introduction:

Harvey C Tian, a highly accomplished inventor and researcher based in Ithaca, NY, has made significant contributions to the field of single cell genomic analysis. With a wealth of patents and expertise in microfluidic devices, Tian's groundbreaking innovations have paved the way for advancements in DNA isolation, amplification, and analysis. Working at Cornell University, Tian has collaborated with esteemed researchers, including his coworkers Harold G Craighead and Juraj Topolancik.

Latest Patents:

Tian's latest patents unveil his cutting-edge work in developing microfluidic devices for single cell whole genome amplification and DNA extraction. These inventions mark a significant leap forward in understanding the genomic complexities of individual cells.

1. Single cell whole genome amplification via micropillar arrays under flow conditions:

This patent introduces a microfluidic device that enables the isolation and amplification of genomic DNA from single cells. The device incorporates a solid substrate with microfluidic channels, including an intake region with a single microchannel, cell segregation microchannels, cell capture sites, and a DNA capture array consisting of micropillars. With this innovation, scientists can perform whole genome amplification and conduct on-chip DNA analysis while ensuring precise control under flow conditions.

2. Microfluidic device for extracting, isolating, and analyzing DNA from cells:

This patent presents a microfluidic device designed specifically for DNA extraction and isolation from cells. Comprising an inlet port, an outlet port, and a microfluidic channel, the device employs a micropillar array to trap and immobilize cells effectively. It further facilitates the elongation or non-elongation of immobilized DNA under hydrodynamic force. The invention holds immense potential for enhancing DNA analysis techniques and streamlining laboratory workflows.

Career Highlights:

Harvey C Tian's innovative work has garnered recognition and acclaim within the scientific community. Through his extensive research at Cornell University, he has contributed significantly to the development of microfluidic devices and their applications in single cell genomic analysis. Tian's patents validate his expertise and exemplify his dedication to advancing the field.

Collaborations:

Tian has had the privilege of collaborating with esteemed researchers during his tenure at Cornell University. Notably, he has worked alongside Harold G Craighead and Juraj Topolancik, both renowned experts in their respective fields. These collaborations have enriched Tian's research and fostered a collaborative environment wherein novel ideas can flourish.

Conclusion:

Harvey C Tian's pioneering contributions to the realm of microfluidic devices have revolutionized the field of single cell genomic analysis. His patented inventions bring forth novel techniques for DNA isolation, amplification, and analysis, propelling scientific research and enhancing our understanding of cellular genomics. With a promising future ahead, Tian continues to push boundaries, addressing new challenges and ushering in the next wave of DNA analysis innovation.