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Years Active: 1992-1995
Title: The Innovative Contributions of Harry A. Crissman
Introduction
Harry A. Crissman is a notable inventor based in Los Alamos, NM (US). He has made significant contributions to the field of biotechnology, particularly in the characterization of chromosomes and the identification of transformed cells. With a total of 3 patents, Crissman's work has implications for both research and therapeutic applications.
Latest Patents
Crissman's latest patents include innovative methods for chromosome characterization and distinguishing between normal and transformed cells. One of his patents, titled "Chromosome characterization using single fluorescent dye," describes a technique where chromosomes are stained with a single dye, such as TOTO or YOYO. This method allows for the identification and sorting of specific chromosomes based on their fluorescent emissions when excited by different wavelengths of light.
Another significant patent is the "Method for distinguishing normal and transformed cells using G1 kinase." This invention involves applying a G1 phase kinase inhibitor to a population of mammalian cells. The inhibitor is used at a concentration that selectively arrests normal cells while allowing transformed cells to grow. This method not only aids in the identification and cloning of transformed cells for research but also suggests potential therapeutic applications in cancer treatment.
Career Highlights
Throughout his career, Harry A. Crissman has worked with esteemed organizations, including the United States of America as represented by the United States and the University of California. His innovative approaches have contributed to advancements in cellular biology and cancer research.
Collaborations
Crissman has collaborated with notable colleagues such as Donna M. Gadbois and Robert A. Tobey. These partnerships have further enriched his research and development efforts in the field.
Conclusion
Harry A. Crissman's contributions to biotechnology through his patents and collaborations highlight his role as an influential inventor. His work continues to impact research and therapeutic strategies in the life sciences.