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Years Active: 2020
Title: Harold C. Riethman: Innovator in Nucleic Acid Detection
Introduction
Harold C. Riethman is a notable inventor based in Chesapeake, Virginia. He has made significant contributions to the field of molecular biology, particularly in the detection of nucleic acids. His innovative methods leverage the CRISPR/Cas technology to enhance the specificity and efficiency of nucleic acid labeling.
Latest Patents
Riethman holds a patent for "Methods of specifically labeling nucleic acids using CRISPR/Cas." This patent outlines a method for detecting a target nucleic acid sequence. The process involves contacting genomic DNA with a guide RNA that is complementary to the target sequence, along with Cas9 nickase to create a single-strand break in the DNA. Following this, the nicked DNA is treated with a polymerase and a fluorescently labeled nucleotide, allowing for the detection of the target sequence through the fluorescent label.
Career Highlights
Throughout his career, Riethman has worked with prestigious institutions such as Drexel University and The Wistar Institute of Anatomy & Biology. His work has been instrumental in advancing the understanding of genetic sequences and their applications in various fields, including diagnostics and therapeutics.
Collaborations
Some of his notable coworkers include Ming H. Xiao and Wenhui Hu. Their collaborative efforts have contributed to the development of innovative techniques in molecular biology.
Conclusion
Harold C. Riethman is a pioneering inventor whose work in nucleic acid detection has the potential to revolutionize the field of genetics. His contributions through patents and collaborations highlight the importance of innovation in scientific research.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.