Brookline, MA, United States of America

Harold Brem

This inventor holds 1 USPTO granted patent. Top assignee: Children's Medical Center Corporation. Active years: 2000.

IDiyas Innovation Intelligence. (2026). Inventor Profile: Harold Brem. Retrieved from https://idiyas.com/inventor/harold-brem-6cc3zuup

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile


% Patents Active = 100.0

Average Co-Inventor Count = 2.0

ph-index = 1

Forward Citations = 14(Granted Patents)


Company Filing History:


Years Active: 2000

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1 patent (USPTO):Explore Patents

Title: Harold Brem: Innovator in Angiogenesis Treatment

Introduction

Harold Brem is a notable inventor based in Brookline, MA, who has made significant contributions to the field of medicine. His work primarily focuses on methods for treating angiogenesis-induced diseases, which are conditions characterized by the growth of new blood vessels.

Latest Patents

Brem holds a patent for "Methods of treating angiogenesis-induced diseases and pharmaceutical." This invention provides for the use of fumagillin or an O-substituted fumagillol derivative in conjunction with interferon. The combination increases the angiogenic inhibitory action compared to the agents administered alone. Furthermore, it has been discovered that this combination is synergistic in its angiogenesis inhibitory effect, offering a promising method for treating various angiogenesis-induced diseases.

Career Highlights

Harold Brem has had a distinguished career, working at the Children's Medical Center Corporation. His innovative approaches have paved the way for advancements in medical treatments, particularly in the area of angiogenesis.

Collaborations

Brem has collaborated with notable figures in his field, including Moses J Folkman, who is recognized for his pioneering work in angiogenesis research.

Conclusion

Harold Brem's contributions to the treatment of angiogenesis-induced diseases highlight his role as a significant inventor in the medical field. His innovative patent demonstrates the potential for improved therapeutic strategies in combating these challenging conditions.

Profile summary based on public USPTO records.
Data Sources: USPTO Patent Grant XML, Patent Center, EPO & CIPO • Normalized by IDiyas Innovation Graph. Methodology & provenance architecturePlease report any incorrect information to [email protected]
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