Harold A Karnes

Title: Harold A. Karnes: Innovator in Pharmaceutical Steroids

Introduction

Harold A. Karnes is a notable inventor based in Kalamazoo, MI (US), recognized for his contributions to the field of pharmaceutical agents. With a total of six patents to his name, he has made significant advancements in the development of steroid compounds.

Latest Patents

Among his latest patents are the "Imidazolylpiperazinyl steroids," which disclose amino substituted steroids that contain an imidazolylpiperazinyl group. This group is attached to the terminal carbon atom of the C.sub.17 -side chain, making these compounds useful as pharmaceutical agents for treating various medical conditions. Another significant patent is the "Triazinylpiperazinyl steroids," which also features amino substituted steroids. These compounds contain a 4-[1,3,5-triazin-2-yl]- or 4-[1,2,4-triazin-3-yl]-1-piperazinyl group, similarly attached to the terminal carbon atom of the C.sub.17 -side chain, and are designed for therapeutic applications.

Career Highlights

Harold A. Karnes has had a distinguished career at The Upjohn Company, where he has focused on innovative research and development in the pharmaceutical sector. His work has contributed to the advancement of steroid-based treatments, showcasing his expertise and commitment to improving healthcare.

Collaborations

Throughout his career, Karnes has collaborated with notable colleagues, including John M. McCall and Donald E. Ayer. These partnerships have fostered a collaborative environment that has led to the successful development of various pharmaceutical innovations.

Conclusion

Harold A. Karnes stands out as a significant figure in the field of pharmaceutical innovation, with a strong portfolio of patents that reflect his dedication to advancing medical treatments. His work continues to impact the industry positively.