Company Filing History:
5 out of 3,539 
2 out of 1,217 
1 out of 254 
Years Active: 1984-2019
Title: Harlan D Caldwell: Innovator in Chlamydia Vaccine Development
Introduction
Harlan D Caldwell is a notable inventor based in Hamilton, Montana, who has made significant contributions to the field of medical research, particularly in the development of vaccines for Chlamydia infections. With a total of nine patents to his name, Caldwell's work focuses on innovative compositions and methods aimed at treating and preventing Chlamydial infections.
Latest Patents
Caldwell's latest patents include a Chlamydia vaccine that discloses compositions and methods for the treatment of Chlamydial infection. The compositions provided include polypeptides that contain at least one antigenic portion of the antigen and DNA sequences encoding such polypeptides. Additionally, pharmaceutical compositions, vaccines, and diagnostic kits are also disclosed. Another significant patent is for an attenuated Chlamydia vaccine, which provides vectors, attenuated pathogens, compositions, methods, and kits for preventing or treating infections caused by infectious pathogens. This invention includes vectors comprising plasmid-encoded ppg genes while lacking ppg4, a regulator of virulence-associated genes. The application also discusses attenuated pathogens that are cured of their plasmid and have additional mutations to enhance attenuation, particularly mutations in the CT135 gene or in the tryptophan operon.
Career Highlights
Caldwell has worked with prestigious organizations, including the National Institutes of Health, a component of the U.S. Department of Health & Human Services, and The United States of America as represented by the Department of Health. His work in these institutions has allowed him to contribute significantly to public health and medical research.
Collaborations
Throughout his career, Caldwell has collaborated with esteemed colleagues, including Yuan Ying and You-Xun Zhang. These collaborations have furthered his research and development efforts in the field of infectious diseases.
Conclusion
Harlan D Caldwell's innovative work in the development of Chlamydia vaccines showcases his dedication to advancing medical science and improving public health. His contributions through patents and collaborations highlight the importance of research in combating infectious diseases.