Hans-Willi Jansen

Title: Innovations of Hans-Willi Jansen in Sodium-Proton-Exchanger Ligand Efficiency

Introduction

Hans-Willi Jansen is a notable inventor based in Frankfurt am Main, Germany. He has made significant contributions to the field of biochemistry, particularly in the area of sodium-proton-exchanger (NHE) ion channels. His work focuses on developing methods to determine the efficiency of ligands that interact with these channels.

Latest Patents

Hans-Willi Jansen holds a patent for "Methods for determining sodium-proton-exchanger ligand efficiency." This invention outlines a systematic approach to assess the in vivo efficiency of NHE ion channel ligands. The method involves several steps, including contacting a cell expressing the NHE ion channel with plasma from an animal and determining the ligand's effect on the cell. The process also includes measuring ligand availability and correlating it with the observed effects to ascertain the ligand's efficiency.

Career Highlights

Jansen is currently associated with Sanofi, a global healthcare company known for its innovative solutions in pharmaceuticals. His work at Sanofi has allowed him to contribute to advancements in drug development and therapeutic strategies.

Collaborations

One of his notable collaborators is Ursula Schindler, with whom he has worked on various projects related to ion channel research.

Conclusion

Hans-Willi Jansen's innovative methods for determining ligand efficiency in sodium-proton-exchanger channels represent a significant advancement in biochemistry. His contributions continue to influence the field and enhance our understanding of ion channel interactions.