Madison, WI, United States of America

Hans W Sollinger

USPTO Granted Patents = 11 

Average Co-Inventor Count = 3.1

ph-index = 4

Forward Citations = 27(Granted Patents)


Company Filing History:


Years Active: 2000-2025

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11 patents (USPTO):Explore Patents

Title: Innovations of Hans W. Sollinger

Introduction

Hans W. Sollinger is a prominent inventor based in Madison, WI (US). He has made significant contributions to the field of gene therapy, holding a total of 11 patents. His work focuses on innovative methods for delivering gene therapy, particularly in the treatment of diabetes and other conditions.

Latest Patents

One of his latest patents is the "In vivo gene therapy delivery procedure and device." This invention provides a 'localizable' systemic gene therapy system that substantially increases the transfection efficiency of gene vectors into targeted tissue cells. It also reduces the escape of gene vectors from the targeted tissue volume, which can waste the vectors and promote undesired immune reactions. The invention allows for simultaneous local electroporation and gene-containing vector injection in a vascularized organ using two double-balloon catheters. These catheters create contained volumes in parallel blood vessels for the introduction of vectors with reduced loss, while electrodes provide electroporation of the cells in the same location.

Another significant patent is the "Hepatocyte based insulin gene therapy for diabetes." This method involves controlling blood glucose levels in mammals by treating hepatocyte cells with various vectors. These vectors include components such as glucose-inducible regulatory elements and liver-specific promoters, which work together to regulate insulin levels in patients effectively.

Career Highlights

Hans W. Sollinger is associated with the Wisconsin Alumni Research Foundation, where he continues to develop groundbreaking technologies in gene therapy. His innovative approaches have the potential to transform treatment methodologies in the medical field.

Collaborations

He has collaborated with notable colleagues, including Tausif Alam and Debra A. Hullett, contributing to advancements in gene therapy and related research.

Conclusion

Hans W. Sollinger's work exemplifies the spirit of innovation in the field of gene therapy. His patents and research efforts are paving the way for new treatment options that could significantly improve patient outcomes.

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