Company Filing History:
Years Active: 2005
Title: Innovations of Hans Rudolf Müller
Introduction
Hans Rudolf Müller is a notable inventor based in Schaffhausen, Switzerland. He has made significant contributions to the field of chemistry, particularly in the synthesis of hypoxanthine derivatives. His work has implications for various applications in pharmaceuticals and biochemistry.
Latest Patents
Müller holds a patent for "Methods of synthesis for 9-substituted hypoxanthine derivatives." This patent outlines an improved method of synthesis that involves several key steps. The process begins with the reaction of aminocyanacetamide with triethyl orthoformate to create an imidoester derivative. Following this, a compound with a reactive amino group is formed, which is linked to a physiologically active moiety. The imidoester is then reacted with this compound to produce a derivative of aminoimidazole-4-carboxamide. The final steps involve forming a six-membered heterocyclic ring and hydrolyzing any esterified groups present.
Career Highlights
Throughout his career, Müller has worked with prominent companies in the pharmaceutical industry, including Merck Eprova AG and Merck & Cie. His experience in these organizations has allowed him to develop and refine his innovative methods in chemical synthesis.
Collaborations
Müller has collaborated with notable colleagues such as Alvin Jerald Glasky and Heinrich Bollinger. These partnerships have contributed to the advancement of his research and the successful development of his patented methods.
Conclusion
Hans Rudolf Müller is a distinguished inventor whose work in the synthesis of hypoxanthine derivatives has made a significant impact in the field of chemistry. His innovative methods and collaborations highlight his contributions to the pharmaceutical industry.