Company Filing History:
Years Active: 1992-1993
Title: The Innovations of Hans-Helmut Henschel
Introduction
Hans-Helmut Henschel is a notable inventor based in Munich, Germany. He has made significant contributions to the field of pharmaceuticals, particularly in the preparation of pure enantiomers and new chemical derivatives. With a total of 2 patents to his name, Henschel's work has implications for drug development and therapeutic applications.
Latest Patents
Henschel's latest patents include a process for preparing the pure enantiomers of lifibrol and its alkyl esters. This innovative method achieves surprisingly good yields by reacting the pure enantiomeric forms of S(-) R(+)-4-(4-tert.butylphenyl)-1,2-epoxy butane with 4-hydroxybenzoic acid alkyl ester at elevated temperatures in DMF, along with the presence of 4-hydroxybenzoic acid alkyl ester sodium salt. The raw reaction product is then separated, allowing for the recovery of stereochemically pure lifibrol ester through recrystallization or the production of pure crystalline forms via mild alkaline saponification followed by acidification. Another significant patent involves new p-oxibenzoic acid derivatives, detailing their preparation and potential use in drugs with hypolipemic effects.
Career Highlights
Henschel is currently associated with Klinge Pharma GmbH, where he continues to innovate in the pharmaceutical sector. His work focuses on enhancing the efficacy and safety of drug formulations through advanced chemical processes.
Collaborations
Henschel has collaborated with notable colleagues such as Friedemann Reiter and Helmut Grill, contributing to a dynamic research environment that fosters innovation and development in pharmaceutical sciences.
Conclusion
Hans-Helmut Henschel's contributions to the field of pharmaceuticals through his patents and collaborative efforts highlight his role as a significant inventor. His work not only advances scientific knowledge but also has practical applications in drug development.