Location History:
- Darmstadt, DE (1978 - 1980)
- Bickenbach, DE (1982)
Company Filing History:
Years Active: 1978-1982
Title: The Innovative Contributions of Hans-Dieter Orth
Introduction
Hans-Dieter Orth, an accomplished inventor from Darmstadt, Germany, has made significant contributions to the field of immunological assays. With a total of three patents to his name, he has showcased his expertise in developing methods and agents for the determination of enzymes, vital for various medical applications.
Latest Patents
Among Hans-Dieter Orth's latest innovations is a groundbreaking method for the immunological determination of enzymes. This process involves incubating anti-enzyme antibodies adsorbed on a water-insoluble carrier with a sample solution containing the enzyme. The enzyme forms a bond with the antibodies while maintaining a reproducible proportion of its activity in the complex. The subsequent steps include removing the sample solution, washing the antibody carrier, and ultimately determining the enzyme activity bonded to the antibodies.
Another notable patent involves the development of antibodies against creatine kinase-M8. These antibodies specifically target the M subunit of CK isoenzymes, which possess a molecular weight ranging between 130,000 and 210,000. They inhibit the enzymatic activity of the M subunit while preserving the activity of the B subunit of any CK-MB that may be present. The production process for these antibodies involves inoculating animals with activated CK-MM and recovering the antibodies through conventional methods.
Career Highlights
Hans-Dieter Orth is currently affiliated with Merck Patent Gesellschaft mit beschränkter Haftung, a reputable company known for its focus on scientific and technological advancements. His work within the company reflects a steadfast commitment to innovation in the Biotech and Pharmaceutical sectors.
Collaborations
Throughout his career, Hans-Dieter Orth has collaborated with distinguished colleagues, notably Norbert Hennrich and Uwe Wurzburg. These partnerships highlight the collaborative spirit prevalent in the field of biotechnology, where knowledge sharing and teamwork lead to groundbreaking discoveries.
Conclusion
In conclusion, Hans-Dieter Orth stands out as a prominent inventor whose patents significantly impact the understanding and measurement of enzymatic activity in biochemical processes. His innovative methods and collaboration with talented peers underline the importance of research and development in driving advancements in healthcare and diagnostics.