Company Filing History:
Years Active: 2005
Title: Hamideh Zakeri: Innovator in Biochemistry
Introduction
Hamideh Zakeri is a notable inventor based in Chesterfield, MO (US). She has made significant contributions to the field of biochemistry, particularly through her research on methionine aminopeptidases. Her work has implications for understanding protein synthesis and enzyme activity.
Latest Patents
Hamideh Zakeri holds a patent for her discovery of the human methionine aminopeptidase type 3. This enzyme plays a crucial role in the co-translational removal of amino terminal methionine residues from nascent polypeptide chains. The newly-discovered MetAP-3 exhibits substrate specificity similar to MetAP-1 and MetAP-2, but it is not inhibited by fumagillin, an irreversible inhibitor of MetAP-2. Additionally, MetAP-3 preferentially localizes to mitochondria, distinguishing it from its counterparts, which accumulate in the cytoplasm. Her patent also encompasses human cDNAs encoding polypeptides comprising MetAP-3, as well as nucleic acid molecules derived from these cDNAs.
Career Highlights
Hamideh Zakeri is associated with Pharmacia Corporation, where she has been able to apply her research in a practical setting. Her work has contributed to advancements in the understanding of enzyme functions and their applications in biotechnology.
Collaborations
Hamideh has collaborated with notable colleagues, including Carolyn J Sympson and Rajeev Aurora. These collaborations have further enriched her research and contributed to the development of innovative solutions in her field.
Conclusion
Hamideh Zakeri's contributions to biochemistry, particularly through her patent on methionine aminopeptidase type 3, highlight her role as an influential inventor. Her work continues to impact the scientific community and advance our understanding of enzyme activity.