Halina Dahlig

Title: Halina Dahlig: Innovator in Pharmaceutical Chemistry

Introduction

Halina Dahlig is a notable inventor based in Warsaw, Poland. She has made significant contributions to the field of pharmaceutical chemistry, particularly through her innovative work on polyene macrolides. Her research has led to the development of compounds that exhibit high pharmacological activity against various fungal infections.

Latest Patents

Halina Dahlig holds a patent for "Salts of N-glycosyl derivatives of polyene macrolides." This patent describes new compounds, specifically N-methylglucamine salts of N-glycosyl derivatives of polyene macrolides, including amphotericin B, polifungin, and nystatin. These compounds are prepared by reacting an amino group containing polyene macrolide with an aldose or ketose mono- or oligosaccharide in an organic solvent medium. The resulting N-glycosyl derivatives are precipitated from the reaction medium and transformed into N-methylglucamine salts, which are then crystallized from higher alkanols, such as n-butanol. This innovative approach has shown promise in treating topical and systemic fungal infections.

Career Highlights

Throughout her career, Halina Dahlig has worked with esteemed institutions, including the Gdańsk University of Technology and the Pharmaceutical Industry Institute. Her work has been instrumental in advancing the understanding and application of polyene macrolides in medicine.

Collaborations

Halina has collaborated with notable colleagues, including Leonard S. Falkowski and Zuzanna Kowszyk-Gindifer. These partnerships have contributed to her research and the successful development of her patented compounds.

Conclusion

Halina Dahlig's contributions to pharmaceutical chemistry, particularly through her innovative patents, highlight her role as a leading inventor in her field. Her work continues to impact the treatment of fungal infections, showcasing the importance of innovation in healthcare.