Company Filing History:
9 out of 416 
4 out of 27 
1 out of 614 
Years Active: 1984-2022
Title: Hajime Takamatsu: Innovator in Pharmaceutical Chemistry
Introduction
Hajime Takamatsu is a prominent inventor based in Tokyo, Japan, known for his significant contributions to pharmaceutical chemistry. With a total of 11 patents to his name, he has made remarkable strides in developing compounds aimed at treating various urinary tract dysfunctions.
Latest Patents
One of his latest patents includes a 2-acylaminothiazole derivative or salt thereof. This invention addresses the need for a compound that serves as an active ingredient in pharmaceutical compositions for preventing or treating urine storage dysfunction, voiding dysfunction, and lower urinary tract dysfunction. The thiazole derivative, substituted with pyrazinylcarbonylamino at the 2-position, acts as an excellent muscarinic M-receptor-positive allosteric modulator. This compound is expected to be beneficial in treating bladder and urinary tract diseases associated with bladder contractions.
Another notable patent involves a pyridine derivative aimed at treating nocturia. The invention focuses on inhibiting the nocturnal activity of placental leucine aminopeptidase (P-LAP), which cleaves AVP. By maintaining or increasing endogenous AVP levels, the compound enhances the antidiuretic effect, thereby reducing the number of nocturnal voids. The (2R)-3-amino-2-{[4-(substituted pyridine)-2-yl]methyl}-2-hydroxy-propanoic acid derivatives have shown excellent P-LAP inhibitory activity, making them promising candidates for treating nocturia.
Career Highlights
Hajime Takamatsu has worked with notable companies in the pharmaceutical industry, including Astellas Pharma GmbH and Kotobuki Pharmaceutical Co. Ltd. His work in these organizations has allowed him to develop innovative solutions for complex medical issues.
Collaborations
Throughout his career, Takamatsu has collaborated with esteemed colleagues such as Yusuke Inagaki and Kenichi Kawaguchi. These partnerships have contributed to the advancement of his research and the successful development of his patented compounds.
Conclusion
Hajime Takamatsu's innovative work in pharmaceutical chemistry has led to the development of valuable compounds for treating urinary tract dysfunctions. His contributions continue to impact the field positively, showcasing the importance of research and innovation in healthcare.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.