Company Filing History:
Years Active: 2009
Title: Haiping Ke: Innovator in Cold Shock Inducible Expression
Introduction
Haiping Ke is a notable inventor based in Highland Park, NJ (US). He has made significant contributions to the field of biotechnology, particularly in the area of protein expression. His innovative work has led to the development of a unique method for producing heterologous polypeptides.
Latest Patents
Haiping Ke holds a patent titled "Cold shock inducible expression and production of heterologous polypeptides." This invention relates to a DNA molecule or vector and a host cell that can be utilized to produce a heterologous polypeptide under conditions that trigger a cold shock response in the host cell. The patent includes a nucleotide sequence encoding the heterologous polypeptide, along with a promoter and 5'-UTR derived from a cold shock inducible gene that directs its expression. Additionally, an AT-rich sequence that enhances translation under cold shock inducible conditions is either present in the coding sequence of the heterologous polypeptide or in an additional element inserted between the coding sequence and the cold shock inducible promoter and 5'-UTR. This innovative approach has the potential to improve the efficiency of protein production in various applications.
Career Highlights
Haiping Ke is currently associated with Takara Bio Inc., where he continues to advance his research and development efforts. His work has garnered attention in the scientific community, contributing to advancements in biotechnology and molecular biology.
Collaborations
Throughout his career, Haiping Ke has collaborated with esteemed colleagues such as Masayori Inouye and Sangita Phadtare. These collaborations have further enriched his research and have led to significant advancements in the field.
Conclusion
Haiping Ke's innovative contributions to the field of biotechnology, particularly through his patent on cold shock inducible expression, highlight his role as a leading inventor. His work continues to influence the production of heterologous polypeptides, showcasing the importance of innovation in scientific research.