Company Filing History:
Years Active: 1993-1997
Title: Haideh Motamedi: Innovator in Gene Expression Technologies
Introduction
Haideh Motamedi is a notable inventor based in Westfield, NJ (US). He has made significant contributions to the field of gene expression technologies, holding 2 patents that showcase his innovative work. His research primarily focuses on the development of expression cassettes and enzymes that enhance gene expression studies.
Latest Patents
Motamedi's latest patents include groundbreaking inventions related to gene expression. One patent is directed towards expression cassettes useful in gene expression studies in both homologous and heterologous Streptomyces strains. This invention specifically involves the construction of two Streptomyces lividans-recombinant strains capable of producing 31-O-desmethylFK-506 O:methyltransferase, which methylates 31-O-desmethylFK-506 to FK-506. Another patent describes a new enzyme, 31-O-desmethyl-FK-506 O-methyltransferase (FKMT), which can specifically and preferentially methylate the C-31 hydroxy group in various compounds. This enzyme can be isolated from a FK-506 producing microorganism, Streptomyces sp. (Merck Culture Collection No. MA 6858) ATCC No. 55098.
Career Highlights
Haideh Motamedi is currently employed at Merck & Company, Inc., where he continues to advance his research in gene expression technologies. His work has been instrumental in developing methods that enhance the production of important compounds through genetic engineering.
Collaborations
Motamedi collaborates with several talented individuals, including Ali Shafiee and Patricia M Cameron, who contribute to his research efforts and innovations.
Conclusion
Haideh Motamedi's contributions to gene expression technologies through his patents and work at Merck & Company, Inc. highlight his role as an influential inventor in the field. His innovative approaches continue to pave the way for advancements in genetic research and applications.