Company Filing History:
Years Active: 2024
Title: Innovations of Inventor Hai Qian
Introduction
Hai Qian is a prominent inventor based in Nanjing, China. He has made significant contributions to the field of pharmaceuticals, particularly in the development of novel peptides and derivatives for medical applications. With a total of 2 patents, his work focuses on innovative solutions for treating diabetes and metabolic disorders.
Latest Patents
Hai Qian's latest patents include the "Long-acting oxyntomodulin hybrid peptide, preparation method therefor, and application thereof." This invention discloses a polypeptide that modifies oxyntomodulin (OXM) by hybridizing it with a peptide sequence of Exenatide. The modification enables the polypeptide to resist DPP-4 enzyme degradation through amino acid changes, while also conjugating fatty acid chains. This results in an OXM hybrid peptide that has a longer pharmacologic action time and improved weight loss effects. The synthesis of this target polypeptide is achieved through an orthogonal protection strategy solid-phase synthesis method, followed by purification and freeze-drying to obtain the final product.
Another significant patent is the "Phenoxyacetic acid derivatives, preparation method thereof and use thereof as medicament." This invention relates to a novel phenoxyacetic acid derivative, which has shown excellent in vivo hypoglycemic activity. The derivative can be utilized in pharmaceutical compositions for preventing or treating diabetes and metabolic syndrome.
Career Highlights
Hai Qian is affiliated with China Pharmaceutical University, where he continues to advance his research and development efforts. His work has garnered attention for its potential impact on diabetes treatment and metabolic health.
Collaborations
Some of his notable coworkers include Wenlong Huang and Chunxia Liu, who contribute to his research endeavors and collaborative projects.
Conclusion
Hai Qian's innovative work in the field of pharmaceuticals highlights his commitment to developing effective treatments for diabetes and metabolic disorders. His patents reflect a deep understanding of peptide chemistry and its applications in medicine.