H Dennis Tolley

Title: H Dennis Tolley: Innovator in Liquid Chromatography

Introduction

H Dennis Tolley is a notable inventor based in Mapleton, UT (US), recognized for his contributions to the field of liquid chromatography. With a total of six patents to his name, Tolley has developed innovative systems that enhance the efficiency and versatility of chromatography techniques.

Latest Patents

One of Tolley's latest patents is the "Integrated column and detector in a module for liquid chromatography." This invention presents a system and method for separating the functions of a liquid chromatography (LC) system into physically distinct systems. This allows for a more versatile LC system, where an LC device provides column liquid solvent, a sample, and a pump and injector that pushes the sample in the solvent to an output port. The attachable module contains a module input port, a column, a heater for the column, and at least one detector for on-column detection. This design enables the sample in the solvent to be pumped through the column to the detector, facilitating the separation, identification, and quantification of substances in the sample.

Another significant patent is the "Simple equilibrium distribution sampling device for GC-MS calibration." This system provides standard mixtures of volatile and semi-volatile organic compounds for simultaneous gas chromatography (GC) and mass spectrometry (MS) calibration in a calibration vial. The calibration mixtures are prepared by diluting calibration analytes in granular polydimethylsiloxane (PDMS), ensuring that most analytes are in the PDMS phase. This method allows for reliable calibration samples to be taken from the headspace vapor in the calibration vial, offering solvent-less sampling, long-time stability, and ease of use.

Career Highlights

Throughout his career, H Dennis Tolley has worked with reputable organizations, including Brigham Young University and Torion Technologies, Inc. His work has significantly impacted the field of chromatography, leading to advancements that benefit both research and industry applications.

Collaborations

Tolley has collaborated with esteemed colleagues such as Milton L. Lee and Paul B. Farnsworth, contributing to the development of innovative solutions in chromatography.

Conclusion

H Dennis Tolley's contributions to liquid chromatography through his patents and collaborations highlight his role as a significant innovator in the field. His work continues to influence advancements in analytical chemistry and related disciplines.