Dallas, TX, United States of America

Guy L James


Average Co-Inventor Count = 5.6

ph-index = 3

Forward Citations = 135(Granted Patents)


Company Filing History:


Years Active: 1996-1999

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3 patents (USPTO):Explore Patents

Title: The Innovative Contributions of Guy L. James

Introduction

Guy L. James is a notable inventor based in Dallas, Texas, recognized for his significant contributions to the field of biochemistry and cancer research. With a total of three patents to his name, he has made strides in the identification of inhibitors that target critical enzymes involved in cancer progression.

Latest Patents

His latest patents include groundbreaking methods for the identification of farnesyltransferase inhibitors. These patents disclose methods and compositions aimed at identifying inhibitors of farnesyltransferase enzymes, which play a crucial role in the prenylation of various cellular proteins, including cancer-related ras proteins such as p21.ras, particularly K-rasB. The patents detail procedures for utilizing purified farnesyltransferase enzymes and K-rasB proteins in screening protocols to identify potential anticancer agents that inhibit the enzyme, thereby preventing the prenylation of proteins like K-RasB.

Career Highlights

Throughout his career, Guy L. James has worked with prestigious organizations, including the University of Texas System and Genentech, Inc. His work has been instrumental in advancing the understanding of cancer biology and developing therapeutic strategies.

Collaborations

He has collaborated with esteemed colleagues such as Michael S. Brown and Joseph L. Goldstein, further enhancing the impact of his research in the scientific community.

Conclusion

Guy L. James exemplifies the spirit of innovation in the field of biochemistry, with his patents paving the way for potential advancements in cancer treatment. His contributions continue to inspire future research and development in this critical area of health.

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