Company Filing History:
4 out of 101 
4 out of 3,221 
3 out of 15,462 
Years Active: 1988-2003
Title: Innovator in Biotechnology: The Contributions of Gustav Ammerer
Introduction: Gustav Ammerer, based in Seattle, WA, is a notable inventor who has made significant strides in the field of biotechnology. With a portfolio of seven patents, his work primarily focuses on the synthesis of human virus antigens using yeast expression systems.
Latest Patents: Among his latest patents, the synthesis of human virus antigens by yeast stands out. This invention relates to the synthesis of Hepatitis B antigen (HB Ag) in yeast. In this process, yeast expression vectors composed of a yeast promoter, ADH1, have been constructed. The coding region for the S-protein of the HBV genome, omitting a possible 163 amino acid presequence, was successfully transferred to the yeast expression vector. This advancement led to the successful synthesis of HB Ag, which has shown antigenic properties by being reactive with anti-HB Ag. Notably, a significant portion of the synthesized product is associated with particles akin to those in the serum of HBV-infected patients, although they are smaller in size. The synthesized HB Ag demonstrated sedimentation behavior that matches that of naturally occurring HB Ag particles purified from Alexander cells as measured by sucrose gradient sedimentation. This patent illustrates the complex assembly of a multi-component structure resulting from the expression of a heterologous DNA coding segment in a microorganism.
Career Highlights: Ammerer has had a remarkable career in research and development. He has notably contributed to projects at esteemed organizations such as the Washington Research Foundation and Genentech, Inc., enhancing the landscape of biotechnological innovations.
Collaborations: Throughout his career, Ammerer has collaborated with prominent professionals, including Benjamin D. Hall and Ronald A. Hitzeman. His teamwork and collaborative spirit have undoubtedly contributed to his success and the impact of his inventions.
Conclusion: Gustav Ammerer’s dedication to innovation in biotechnology has led to important advancements in the synthesis of virus antigens. With his impressive patent portfolio and collaborations with leading researchers, Ammerer continues to be a pivotal figure in the realm of biotechnology, influencing future developments and research in healthcare and beyond.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.