Company Filing History:
Years Active: 2001
Title: The Innovations of Gurparlash Singh: A Look at His Transgenic Mouse Patent
Introduction
Gurparlash Singh, based in Bedminster, NJ, is an accomplished inventor recognized for his significant contributions to the field of biotechnology. With a focus on transgenic models, Singh has developed groundbreaking inventions that help advance research on neurodegenerative diseases. His notable patent, dealing with a specific variant of human amyloid precursor protein, has the potential to pave the way for new therapeutic strategies.
Latest Patents
Gurparlash Singh holds a patent for a transgenic mouse designed to express a familial form of human amyloid precursor protein. The specific variant involves a DNA sequence where, at amino acid position 717, valine is replaced by isoleucine. This innovative transgenic model serves as an assay system, facilitating the determination of compounds that can modulate the production of human amyloid precursor protein in the brain and isolated neuronal cells. The patent exemplifies the capabilities of transgenic mice to produce the APP-FAD variant, verified through mRNA and protein assays.
Career Highlights
Currently, Gurparlash Singh is working with Merck & Company, Inc., where he continues to push the boundaries of scientific research through innovative projects. His expertise in molecular biology and genetics has not only contributed to valuable research within the company but has also positioned him as a leading inventor of transgenic models beneficial for studying Alzheimer's disease.
Collaborations
Throughout his career, Gurparlash Singh has collaborated with notable coworkers, including Howard Y. Chen and Robert P. Heavens. These partnerships emphasize the importance of teamwork in advancing research and developing innovative solutions to complex biological problems.
Conclusion
Gurparlash Singh's work exemplifies the vital role of inventors in scientific progress. His patent for a transgenic mouse model represents a crucial step toward understanding and treating debilitating conditions like Alzheimer's disease. As he continues his research at Merck & Company, Inc., Singh's contributions will undoubtedly have lasting impacts on biotechnology and pharmaceuticals in the years to come.