Location History:
- La Jolla, CA (US) (1997 - 1999)
- Miami, FL (US) (1999 - 2001)
Company Filing History:
Years Active: 1997-2001
Title: Gunter Kraus: Innovator in HIV-Based Gene Therapy
Introduction
Gunter Kraus is a prominent inventor based in Miami, FL, known for his significant contributions to the field of gene therapy. With a total of 6 patents to his name, Kraus has focused on developing innovative solutions for HIV-based packaging systems that enhance gene delivery methods.
Latest Patents
Kraus's latest patents include the design of novel highly efficient HIV-based packaging systems for gene therapy. By transducing cells with an HIV-1-MN molecular clone deleted in the major packaging sequence, he produced a stable HIV-1 packaging cell line, &psgr;422. This cell line forms syncytia with CD4 positive cells, correctly expresses HIV-1 structural proteins, and produces large amounts of mature particles with normal reverse transcriptase activity. Importantly, these particles are non-infectious. When stably transfected with an HIV-based retroviral vector, the &psgr;422 cell line generates hybrid virions capable of transducing CD4 positive cells with high efficiency, enabling the use of HIV-1 based nucleic acid delivery systems in gene therapy. Additionally, his work includes the development of novel HIV-2 proviruses, molecular clones, nucleic acids, polypeptides, and viral components, which have applications in diagnostic assays, immunological reagents, vaccines, and gene therapy vectors.
Career Highlights
Kraus has made significant strides in the field of biotechnology, particularly in the development of non-infectious HIV packaging systems. His innovative approaches have paved the way for safer and more effective gene therapy techniques. His work is recognized for its potential to transform the landscape of HIV treatment and gene therapy.
Collaborations
Throughout his career, Kraus has collaborated with notable scientists, including Flossie Wong-Staal and Eric M Poeschla. These collaborations have further enhanced the impact of his research and innovations in the field.
Conclusion
Gunter Kraus stands out as a key inventor in the realm of HIV-based gene therapy, with a focus on creating efficient and safe packaging systems. His contributions are vital for advancing gene therapy techniques and improving treatment options for patients.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.