Guido Trione

Title: Guido Trione: Innovator in Antibiotic Production

Introduction

Guido Trione is a notable inventor based in Rodano, Italy. He has made significant contributions to the field of antibiotic production, holding 2 patents that showcase his innovative approaches. His work focuses on improving fermentation processes for the production of essential antibiotics.

Latest Patents

Trione's latest patents include a procedure for the production of tiacumicin B. This invention involves the fermentation of a microorganism capable of producing tiacumicin B, particularly of the species in a culture broth containing emulsifiers, such as ethoxylated castor oil, combined with antifoaming products and vegetable oils. Another significant patent is for an improved process for the production of daptomycin. This process utilizes fermentation in the presence of n-decanal or oil as sources of the n-decanoyl side chain. These reagents help reduce toxicity effects on bacteria and eliminate the need for solvents in the feeding solution.

Career Highlights

Throughout his career, Trione has worked with prominent companies in the pharmaceutical industry, including Antibioticos S.p.A. and Olon S.p.A. His experience in these organizations has allowed him to refine his expertise in antibiotic production and fermentation processes.

Collaborations

Trione has collaborated with several professionals in his field, including Antonella Malcangi and Gianluca Bertetti. These collaborations have contributed to the advancement of his research and the successful development of his patented processes.

Conclusion

Guido Trione's innovative work in antibiotic production has led to significant advancements in the field. His patents reflect a commitment to improving fermentation processes, which are crucial for the development of effective antibiotics.